Measurement of excitation-inhibition ratio in autism spectrum disorder using critical brain dynamics
نویسندگان
چکیده
منابع مشابه
PT698. Shifting Excitation/Inhibition Balance in Autism Spectrum Disorder
Background: Opioid sensitivity is well known to vary widely among individual subject in levels of μ-opioid receptor (MOP) expression, responses to pain and analgesic effect of morphine. Many studies have reported that the single nucleotide polymorphism (SNP), A118G, of the μ-opioid receptor gene (OPRM1) has been shown to be associated with MOP expression levels, as well as pain thresholds, anal...
متن کاملHow local excitation-inhibition ratio impacts the whole brain dynamics.
The spontaneous activity of the brain shows different features at different scales. On one hand, neuroimaging studies show that long-range correlations are highly structured in spatiotemporal patterns, known as resting-state networks, on the other hand, neurophysiological reports show that short-range correlations between neighboring neurons are low, despite a large amount of shared presynaptic...
متن کاملOPINION Brain connectivity in autism spectrum disorder
Many studies have reported that individuals with autism spectrum disorder (ASD) have different brain connectivity patterns compared with typically developing individuals. However, the results of more recent studies do not unanimously support the traditional view in which individuals with ASD have lower connectivity between distant brain regions and increased connectivity within local brain regi...
متن کاملInfluence of Excitation/Inhibition Imbalance on Local Processing Bias in Autism Spectrum Disorder
People with autism spectrum disorder (ASD) tend to detect local patterns of visual stimuli more quickly than global patterns, which is opposite to the behavior of typically developing people. We hypothesized that the imbalance between excitation and inhibition neurons in the visual cortex causes the local processing bias observed in ASD. Stronger inhibitory connections could diminish the neural...
متن کاملComparison of Motor Skills in At-risk with Autism Spectrum Disorder Children with Autism Spectrum Disorder and Typical Development Children
Background: Autism Spectrum Disorder (ASD) is a complex developmental disorder characterized by repetitive and stereotypical patterns, and difficulties with social communication and interaction in early childhood. Motor development and dysfunction in children with ASD has been the subject of study in recent years and has attracted much of the attention of researchers. As motor dysfunctions can ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2020
ISSN: 2045-2322
DOI: 10.1038/s41598-020-65500-4